Drug Class And Mechanism: Letrozole is an oral, anti-estrogen drug that is
used for treating postmenopausal women with breast cancer. The growth of
some breast cancers in postmenopausal women is promoted by estrogens that
circulate in the blood, and the adrenal glands are the main source of
these circulating estrogens. Letrozole inhibits the enzyme in the adrenal
glands (aromatase) that produces the estrogens, estradiol and estrone.
Letrozole was approved by the FDA in 1997.
Prescribed For: Letrozole infertility is used to treat postmenopausal
women with breast cancer that is resistant to the more commonly-used
anti-estrogen medications such as tamoxifen (Nolvadex). It also is
approved for treating postmenopausal women after surgery who have
hormone-sensitive early breast cancer.
How Should I Take This Medicine?
Take letrozole tablets by mouth at the same time each day. Follow the
directions on the prescription label. Swallow the tablets with a drink of
water. Do not take your medicine more often than directed. Do not stop
taking except on your prescriber's advice.
Dosing: Letrozole generally is taken once daily, with or without food.
Storage: Tablets should be stored at room temperature, 15-30 °C (59-86
°F).
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Prescription Needed) that got great feedback from our
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I am very grateful for this drug. I am cancer free after 5 years. April.
Appears it is working. I was Stage IIA Breast Cancer with 2/12 lymph nodes
involved. Erika.
Arimadex gave me trigger fingers. Couldn't open my hands without my ring
fingers sticking. Much better since I am on Letrozole. Keith.
Great for keeping my TM down - my CEA range from 2.4 to 2.7 and the
CA27.29 ranges from 44 to 48, tumor not growing. Letrozole definitely is
managing my progression and I am happy with the results. Monica.
Got relief for most of the side effects by taking Glucosamin, Chondroitin,
MSM pills for joints and it helped greatly. Am taking Replens and Ovestin
cream for vaginal dryness,and have succeeded in having a sex life, even
though less exciting. I have taken Letrozole for a year and a half after
five years of Tamoxifen. No recurrence of Cancer, worth everything. Molly.
Cancer has not come back even though I am Stage IIIB with 10 of 16 lymph
nodes positive and a very aggressive form of breast cancer. I think loss
of both breasts increased my depression and loss of libido so can't blame
it all on Letrozole. Have just finished taking Letrozole after 5 years. I
am currently not on any drug. Doctor said no additional benefit from
taking Letrozole more than 5 years. Hope she's right and my NED status
lasts. Jenna.
It has kept my bone metastisis stable for 16 months which has allowed me
to delay chemotherapy or additional radiation. Julia.
*The testimonials shown above are based on actual letters we received from
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